The disease Cystic Fibrosis (C.F for short) is called in Hebrew “cystic fibrosis”.
Cystic fibrosis, CF, is a genetic, autosomal recessive disease manifested as a multisystem disease. It is one of the more common genetic diseases in 1 in 2500 white babies.
Cystic fibrosis, CF, is caused by a defect in the CFTR protein (CTR) (Cystic Fibrosis Transmembrane Conductance Regulator) located on chromosome 7, which interferes with the transfer of ions, especially chlorine and sodium (salt) through epithelial cells (expectant cells). The body tubes).
Due to the poor secretion of chlorine and sodium from the tubes, there is no absorption of fluids, and the secretions become viscous and cause blockages in all kinds of systems in the body, such as the airways, bile ducts, pancreas, and the male reproductive system. The sweat glands and saliva have an increased secretion of salt, which causes salty sweat. There is a danger of increased loss of fluids and salts to a state of dehydration.
Airway obstruction causes recurrent infections with a severe inflammatory response and the slow destruction of the airways and lungs. The blockage in the pancreas causes the secretion of enzymes into the intestines essential for the absorption of food. Therefore, if you do not take artificial enzymes, there may be a problem of malnutrition and multiple bowel movements.
The disease is manifested in the following symptoms:
– stubborn cough and multiple phlegm. Healthy.
– Abnormal bowel activity, sometimes chronic diarrhea, frequent bowel movements, bulky, oily, and spreads a bad odor.
– salty taste of the skin. And habits.
Each of these symptoms is not only specific to CF. They may also appear in other diseases. However, when many of the symptoms appear together, they serve as a hint to the doctor and make it easier for him to make an accurate diagnosis.